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MODERN RHEUMATOLOGY Vol.14 No.2

>MR14-2

Autoimmune hepatitis in a patient with systemic lupus erythematosus: a case report
Satoshi Yamasaki1, Tomoki Origuchi2 , Keisuke Nakata1, Kan Toriyama3, Takashi Taguchi4, Hiroaki Ida1, Atsushi Kawakami1 and Katsumi Eguchi1
(1) First Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan
(2) Nagasaki University School of Health Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8520, Japan
(3) Department of Pathology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
(4) Second Department of Pathology, Nagasaki University School of Medicine, Nagasaki, Japan
Received: 06 February 2003 Accepted: 29 August 2003

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Abstract

 A 48-year-old woman was admitted to our hospital because of ascites. Laboratory data indicated the presence of systemic lupus erythematosus (SLE) with nephrotic syndrome and elevated hepatic enzymes. Treatment with prednisolone resulted in a marked clinical improvement in renal and liver dysfunction. Histopathologic analysis of renal and liver tissues showed lupus nephritis and liver cirrhosis, respectively. According to the autoimmune hepatitis scoring system, the patient had both SLE and autoimmune hepatitis.
 
Key words
Autoimmune hepatitis - Scoring system - Systemic lupus erythematosus (SLE)
 
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