| |
|
 |
|
MODERN RHEUMATOLOGY Vol.13 No.3
>MR13-3
|
| Assessment of inflamed synovial membrane in the knee joint by dynamic magnetic resonance imaging |
| |
| Mitsumasa Kawai1, Akito Nishimura2, Toshiaki Ikeda1, Hirahito Endo3, Miyoko Rana3, Moritoshi Itoman4 and Kiyoko Sakurai1 |
(1) Kitasato University Graduate School of Medical Science, 1-15-1 Kitasato, Sagamihara, 228-8555, Japan
(2) Division of Orthopedic Surgery, Nakaizu Spa Hospital, Tagata-gun, Shizuoka, Japan
(3) Department of Internal Medicine, School of Medicine, Kitasato University, Sagamihara, Japan
(4) Department of Orthopedic Surgery, School of Medicine, Kitasato University, Sagamihara, Japan
(5) Present address: 6-3-3-1308 Fujimi, Sagamihara, 229-0036, Japan |
| |
| Received: 01 October 2002 Accepted: 19 December 2002 |
| |
Full Text
> Click Here （member's only） |
| |
| Abstract |
| Dynamic magnetic resonance imaging (dynamic MRI) was used to examine the synovial membrane in the knee joints of 15 patients with rheumatoid arthritis (RA) in order to investigate the relationship between pathological and MRI findings. Signal intensities in the regions of interest (ROI), identified as the synovial membrane of the suprapatellar pouch, were measured on MR images. Signal intensities at various times after the injection of contrast medium Gd?diethylenetriaminopentoacetic acid (Gd?DTPA) were normalized relative to the signal intensity at 80s, and designated as the normalized signal intensity (NSI). Pathological findings were quantified, and the types of inflamed synovial membrane were classified as either acute or chronic. A significant difference in NSI was observed between acute and chronic types (P 0.05). Dynamic MRI was capable of classifying acute and chronic RA by measuring NSI 20s after contrast medium injection. Dynamic MRI was therefore shown to be useful for assessing regional synovial inflammation. |
| |
| Key words |
| Dynamic magnetic resonance imaging (Dynamic MRI) - Gd-diethylenetriaminopentoacetic acid (Gd?DTPA) - Normalized signal intensity (NSI) - Rheumatoid arthritis (RA) - Suprapatellar pouch |
|
| |
| 一覧に戻る |
|
|
