Pulmonary AL amyloidosis in a patient with primary Sjogren syndrome
S. Banno2, Y. Matsumoto1, Y. Hayami1, Y. Sugiura1, T. Yoshinouchi1 , R. Ueda1
(1)Second Department of Internal Medicine, Medical School, Nagoya City University, Nagoya, Japan
(2) Department of Clinical Laboratory Medicine, Medical School, Nagoya City University, 1 Kawasumi, Mizuho-ku, Nagoya 460-8601, Japan
Abstract The condition of a 29-year-old woman with primary Sjogren syndrome (SS) was complicated by amyloid light chains- (AL-) type amyloidosis in the paranasal sinus. She had not complained of respiratory symptoms, but her chest computed tomography (CT) scan revealed bilateral multiple nodular shadows. Lung biopsy specimens using video-associated thoracoscopy showed amyloidoma in a subpleural nodular lesion and amyloid deposits in the interstitial parenchymal walls and pulmonary vessels. Pulmonary AL amyloidosis, presumably related to a chronic inflammatory lymphoproliferative process in SS, has rarely been reported.
Key words
Key words Pulmonary amyloidosis ・ Sjogren syndrome (SS)
