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MODERN RHEUMATOLOGY Vol.11 No.3

>MR11-3

A case of malignant fibrous histiocytoma on the knee joint in a patient with rheumatoid arthritis
K. Matsui1, M. Terada1, K. Tominaga1, Y. Shigenobu1, T. Nishigami2, K. Uematsu2, T. Hada1
(1)Third Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan
(2)Second Department of Pathology, Hyogo College of Medicine, Nishinomiya, Japan
 
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Abstract
Abstract An elderly woman with rheumatoid arthritis and receiving nonsteroidal anti-inflammatory drugs (NSAIDs) treatment was diagnosed with a malignant fibrous histiocytoma in her left knee joint. However, no metastatic lesion caused by the malignant fibrous histiocytoma was found, probably owing to the NSAIDs therapy. Her general condition worsened, and eventually led to renal failure and death from progressive respiratory failure caused by pulmonary effusion. This is the first known report of a malignant fibrous histiocytoma originating in the left knee joint that was complicated by rheumatoid arthritis.
 
Key words
Key words Malignant fibrous histiocytoma ・ Rheumatoid arthritis
 
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