Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review

Vol.21 No.4

Case Report

Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review

Authors

Yasuhiro Shimojima¹ , Wataru Ishii¹ , Masayuki Matsuda¹ , Kana Tojo¹ , Rie Watanabe¹ , Shu-ichi Ikeda¹

Third Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan

Received:

29 September 2010

Accepted:

14 December 2010

Published online:

15 January 2011

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Abstract

We report a patient with neuropsychiatric systemic lupus erythematosus (NPSLE) complicated by diabetes mellitus (DM) who showed pneumatosis cystoides intestinalis (PCI) while being treated with prednisolone (PSL) and an alpha-glucosidase inhibitor (αGI). The PCI was ameliorated with the cessation of the αGI and tapering of PSL in addition to transient fasting. Multiple factors, including NPSLE, DM, and medications, may have been involved in the pathogenesis of PCI in this patient.

Key words

Alpha-glucosidase inhibitor - Corticosteroid - Diabetes mellitus - Pneumatosis cystoides intestinalis - Systemic lupus erythematosus