Cutaneous polyarteritis nodosa in a patient with Crohn’s disease
Atsushi Komatsuda1 , Koji Kinoshita1 , Masaru Togashi1 , Nobuki Maki1 , Rie Masai1 , Hidetaka Niitsu2 , Setsuya Ohtani3 , Masato Sageshima4 , Ken-ichi Sawada1 , Hideki Wakui1
16 April 2008
30 June 2008
20 August 2008
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A 19-year-old Japanese woman with a 4-year history of Crohn’s disease (CD) developed high fever, polyarthralgia, and painful subcutaneous nodules of the legs. A skin biopsy showed panarteritis with fibrinoid necrosis in the deep dermis. Endoscopic examination showed aphthous lesions in the entire colon. She was diagnosed with cutaneous polyarteritis nodosa (PAN) associated with CD. Steroid therapy improved her symptoms. To our knowledge, this is the first Japanese case of cutaneous PAN associated with CD.
Crohn’s disease - Subcutaneous nodules - Inflammatory bowel disease - Polyarteritis nodosa